反应详情

温度

50 °C

A mixture of 1-acetylaminoanthraquinone (purity 99.9%, 26.5 g), monochlorobenzene (320 g), tetra-n-butyl ammonium bromide (0.3 g) and 96% potassium hydroxide (12.0 g) was stirred for 30 minutes while being maintained at 50° C. Then, dimethylsulfuric acid (25.2 g) was dropped at 50° C. over 2 hours. The solution was stirred at 50° C. for 30 minutes, 60° C. for 2 hours and 70° C. for 4 hours, successively. After water (150 g) was added, the solution was stirred for 1 hour while being maintained at 50° C. Then, the same procedure as in Example 3 was carried out to obtain N-acetyl-1-methylaminoanthraquinone (27.9 g, purity 93.6%, yield 93.6%).

1. stirringThe solution was stirred at 50° C. for 30 minutes, 60° C. for 2 hours and 70° C. for 4 hours
2. stirringthe solution was stirred for 1 hour
3. temperaturewhile being maintained at 50° C