참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | Dimethyl Sulfate | HCID 6497 | — |
| 반응물 | Sodium Hydroxide | HCID 14798 | — |
| 반응물 | N-(4-Bromo-9,10-dioxo-9,10-dihydroanthracen-1-YL)acetamide | HCID 7730236 | — |
| 촉매 | Tetrabutylammonium Bromide | HCID 74236 | — |
| 용매 | Chlorobenzene | HCID 7964 | — |
| 생성물 | Acetamide, N-(4-bromo-9,10-dihydro-9,10-dioxo-1-anthracenyl)-N-methyl- | HCID 80770 | 95.5% |
반응 단계
A mixture of 4-bromo-1-acetylaminoanthraquinone (purity 98%, 35.1 g), monochlorobenzene (420 g), tetra-n-butyl ammonium bromide (0.3 g) and 98.5% sodium hydroxide (8.1 g) was stirred for 1 hour, while being maintained at 30° C. Then, dimethylsulfuric acid (25.2 g) was dropped at 30° C. over 2 hours. The mixture was stirred at 30° C. for 30 minutes, 40° C. for 2 hours and 50° C. for 4 hours, successively. Then, the same after treatment as in Example 3 was conducted to obtain 4-bromo-N-acetyl-1-methylaminoanthraquinone (34.9 g, purity 93.7%, yield 91.3%).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US05017713 |
|---|
| 출처 데이터셋 | uspto-grants-1991_05 |
|---|
| ORD ID | ord-acb0f45d6e68458bb9499c4d64d54769 |
|---|
| 출처 메모 | uspto-grants-1991_05 |
|---|
