反应详情

温度

30 °C

A mixture of 4-bromo-1-acetylaminoanthraquinone (purity 98%, 35.1 g), monochlorobenzene (420 g), tetra-n-butyl ammonium bromide (0.3 g) and 98.5% sodium hydroxide (8.1 g) was stirred for 1 hour, while being maintained at 30° C. Then, dimethylsulfuric acid (25.2 g) was dropped at 30° C. over 2 hours. The mixture was stirred at 30° C. for 30 minutes, 40° C. for 2 hours and 50° C. for 4 hours, successively. Then, the same after treatment as in Example 3 was conducted to obtain 4-bromo-N-acetyl-1-methylaminoanthraquinone (34.9 g, purity 93.7%, yield 91.3%).

1. stirringThe mixture was stirred at 30° C. for 30 minutes, 40° C. for 2 hours and 50° C. for 4 hours