反应详情

To a methanol solution containing 2 g of 8-hydroxy-5-methyl-1,2,3,4,4a,9a-hexahydro-9-fluorenone in 20 ml of methanol was added 7.18 ml of methanol solution of 40% methylamine and the mixture was refluxed under heating for 5 hours. After left to stand for cooling, the solvent was removed by concentration and the residue was recrystallized from ethanol to obtain 0.35 g of 8-hydroxy-5-methyl-9-methylimino-1,2,3,4,4a,9a-hexahydrofluorene.

1. temperaturethe mixture was refluxed
2. temperatureunder heating for 5 hours
3. waitAfter left
4. temperaturefor cooling
5. customthe solvent was removed by concentration
6. customthe residue was recrystallized from ethanol