Cyclobutylamine → HCID 14988397, compound

Participants

Reaction Steps

A solution of 0.75 g (4.62 mmol) of (R)-2-(tetrazolo [1,5-a]pyrid 6-yl)oxirane and 1.838 ml (22.8 mmol) of cyclobutyl amine in 1.8 ml of absolute ethanol was heated at 100° C. in a sealed reaction tube for 2 hours. The reaction mixture was concentrated to dryness under reduced pressure, wt. 0.997 g. Tlc, mass spectrum and 1H NMR spectra are consistent with good purity and chemical structure.

Provenance & Evidence