HCID 53663276, compound → HCID 53946144, compound

HRID 2051508Notes

Reaction equation

HRID 2051508 reaction equation
[CH2:1]([O:3][C:4](=[O:18])[CH:5]=[CH:6][C:7]1([CH3:17])[C:16]2[C:11](=[CH:12][CH:13]=[CH:14][CH:15]=2)[CH2:10][CH2:9][CH2:8]1)[CH3:2].[H][H]>C(O)C.[Pd]>[CH2:1]([O:3][C:4](=[O:18])[CH2:5][CH2:6][C:7]1([CH3:17])[C:16]2[C:11](=[CH:12][CH:13]=[CH:14][CH:15]=2)[CH2:10][CH2:9][CH2:8]1)[CH3:2]

Participants

5

Reactant 2

HCID 53663276HCID 53663276, compoundHCID 178418361HCID 178418361, compound

Product 1

HCID 53946144HCID 53946144, compound

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 702EthanolSolvent

Procedure

A solution of 21 g of 4 in 200 ml ethanol was hydrogenated in the presence of 2 g 5% Pd on carbon. After the take-up of hydrogen was complete, the catalyst was filtered off and the filtrate evaporated. This yielded 21 g of colourless oil; Rf =0.42 (hexane/ethyl acetate 9/1).

Workup

  1. filtrationthe catalyst was filtered off
  2. customthe filtrate evaporated

Sources & evidence

ORD record
ord-1df8e70f763c4af9a4ec184c9b3105ed
Source dataset
uspto-grants-1991_05
Patent number
US05019585

Reaction notes

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