2-Bromopropane → HCID 20379125, compound

HRID 2051602Notes

Reaction equation

HRID 2051602 reaction equation
BrC(C)C.[OH:5][CH:6]([C@H:10]1[CH2:15][CH2:14][C@H:13]([C:16]([CH3:19])([CH3:18])[CH3:17])[CH2:12][CH2:11]1)[CH:7]([CH3:9])[CH3:8]>>[OH:5][CH:6]([CH:10]1[CH2:11][CH2:12][CH:13]([C:16]([CH3:18])([CH3:17])[CH3:19])[CH2:14][CH2:15]1)[CH:7]([CH3:9])[CH3:8]

Participants

3

Reactant 2

HCID 63582-BromopropaneHCID 178450573HCID 178450573, compound

Product 1

HCID 20379125HCID 20379125, compoundYield 73%

Procedure

This compound was similarly prepared using 2-bromopropane. Distillation of the product yielded a 1:1 mixture of cis and trans-1-(1-hydroxy-2-methylprop-1-yl)-4-t-butylcyclohexane; 77 g, 73% yield; bp 98-110 (3 mm); mol wt 212 (ms); nmr, 0.82 (15 H,s, t-butyl and isopropyl methyl H), 3.0-3.8 (1H, broad, αH); ir, 3360, 1360, 1110, 1000, 980.

Workup

  1. customThis compound was similarly prepared
  2. distillationDistillation of the product
  3. customyielded

Sources & evidence

ORD record
ord-5407e66c4e724407910ba04a2c2d6c0e
Source dataset
uspto-grants-1980_01
Patent number
US04181631

Reaction notes

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