alpha,alpha'-Dichloro-p-xylene → HCID 11138699, compound

HRID 2051668Notes

Reaction equation

HRID 2051668 reaction equation
[C:1]1([CH2:9]Cl)[CH:6]=[CH:5][C:4]([CH2:7]Cl)=[CH:3][CH:2]=1.[C:11]([O-:14])(=[O:13])[CH3:12].[K+]>C(O)(=O)C>[C:11]([O:14][CH2:9][C:1]1[CH:6]=[CH:5][C:4]([CH2:7][O:14][C:11](=[O:13])[CH3:12])=[CH:3][CH:2]=1)(=[O:13])[CH3:12]

Participants

4

Reactant 2

HCID 12171alpha,alpha'-Dichloro-p-xyleneHCID 517044Potassium Acetate

Product 1

HCID 11138699HCID 11138699, compoundYield 63%

Reagents, catalysts & solvents 1

HCID 176Acetic AcidSolvent

Procedure

438 gms (2.5 moles) of p-xylylene dichloride were added slowly to a refluxing solution of 539 gms (5.5 moles) of anhydrous potassium acetate in 2000 mls of glacial acetic acid. The resultant mixture was refluxed for a further 2 hours and then cooled. The solution was extracted several times with hot benzene, and the benzene extracts were washed with water until neutral. After distilling off the benzene, the residue was recrystallised from petroleum ether to yield 350 gms of p-xylylene diacetate.

Workup

  1. temperaturecooled
  2. extractionThe solution was extracted several times with hot benzene
  3. washthe benzene extracts were washed with water until neutral
  4. distillationAfter distilling off the benzene
  5. customthe residue was recrystallised from petroleum ether

Sources & evidence

ORD record
ord-eb427bb715bb40f29005e330a46fa367
Source dataset
uspto-grants-1980_01
Patent number
US04181791

Reaction notes

Loading…