Chlorodiphenylmethane → HCID 12798409, compound

HRID 2051713Notes

Reaction equation

HRID 2051713 reaction equation
C([N:4]1[CH:8]=[C:7]([C:9]([O:11][CH3:12])=[O:10])[N:6]=[CH:5]1)(=O)C.[CH:13](Cl)([C:20]1[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=1)[C:14]1[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=1>C(#N)C>[CH:13]([N:6]1[C:7]([C:9]([O:11][CH3:12])=[O:10])=[CH:8][N:4]=[CH:5]1)([C:14]1[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=1)[C:20]1[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=1

Participants

4

Reactant 2

HCID 7035ChlorodiphenylmethaneHCID 20377958HCID 20377958, compound

Product 1

HCID 12798409HCID 12798409, compound

Reagents, catalysts & solvents 1

HCID 6342AcetonitrileSolvent

Procedure

1.7 g (0.01 mol) of 1-acetyl-4-methoxycarbonyl-imidazole in 5 cc of acetonitrile and 2 g of benzhydryl-chloride were refluxed for 4 hours, the solvent was removed under reduced pressure and the residue was stirred with 15 cc of 0.5 N sodium acetate solution to split off the acetyl group. The 1-benzhydryl-5-methoxycarbonyl-imidazole, m.p. 129° C., was recrystallized from chloroform.

Workup

  1. customthe solvent was removed under reduced pressure
  2. customto split off the acetyl group
  3. customThe 1-benzhydryl-5-methoxycarbonyl-imidazole, m.p. 129° C., was recrystallized from chloroform

Sources & evidence

ORD record
ord-3ae9f0a5165e48f4b96ea0be45e396ca
Source dataset
uspto-grants-1980_01
Patent number
US04182624

Reaction notes

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