反应详情

A solution of 4.2 g of m-chloroperbenzoic acid in 100 ml of methylenechloride was added dropwise at 0°-5° to 4.3 g of 2-(methylthio)-1H-naphth[2,3-d]imidazole in 500 ml of methylenechloride. The reaction solution was stirred for 90 minutes at 0°, washed twice with aqueous potassium bicarbonate solution and once with saturated sodium chloride solution, dried over magnesium sulphate, and concentrated by evaporation on a rotary evaporator. Crystallisation from acetonitrile gave 2.3 g of 2-(methylsulphinyl)-1H-naphth[2,3-d]imidazole having a m.p. of 194°.

1. washwashed twice with aqueous potassium bicarbonate solution and once with saturated sodium chloride solution
2. dry with materialdried over magnesium sulphate
3. concentrationconcentrated by evaporation on a rotary evaporator
4. customCrystallisation from acetonitrile