Hexylamine → HCID 53881303, compound

HRID 2051807Notes

Reaction equation

HRID 2051807 reaction equation
O=[CH:2][C@@H:3]([C@H:5]([C@@H:7]([C@@H:9]([CH2:11][OH:12])[OH:10])[OH:8])[OH:6])[OH:4].[CH2:13]([NH2:19])[CH2:14][CH2:15][CH2:16][CH2:17][CH3:18].[Cl:20][CH2:21][CH2:22][N:23]=[C:24]=[O:25]>>[Cl:20][CH2:21][CH2:22][NH:23][C:24]([N:19]([CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH3:18])[CH:2]1[O:10][C@H:9]([CH2:11][OH:12])[C@@H:7]([OH:8])[C@H:5]([OH:6])[C@H:3]1[OH:4])=[O:25]

Participants

4

Reactant 3

HCID 8102HexylamineHCID 160352-Chloroethyl isocyanateHCID 107526(2R,3S,4R,5R)-2,3,4,5,6-pentahydroxyhexanal

Product 1

HCID 53881303HCID 53881303, compoundYield 92.3%

Procedure

3.6 g of D-glucose, 2.5 g of n-hexylamine and 2.5 g of 2-chloroethyl isocyanate are treated in the same manner as described in Example 5-(1). 6.8 g of 1-(2-chloroethyl)-3-n-hexyl-3-D-glucopyranosylurea are thereby obtained as brownish caramel.

Sources & evidence

ORD record
ord-af71577498d540b3b0db7924475ea040
Source dataset
uspto-grants-1980_01
Patent number
US04182757

Reaction notes

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