Isobutylamine → HCID 54093436, compound

HRID 2051816Notes

Reaction equation

HRID 2051816 reaction equation
O=[CH:2][C@@H:3]([C@H:5]([C@H:7]([C@@H:9]([CH2:11][OH:12])[OH:10])[OH:8])[OH:6])[OH:4].[CH2:13]([NH2:17])[CH:14]([CH3:16])[CH3:15].[Cl:18][CH2:19][CH2:20][N:21]=[C:22]=[O:23]>>[Cl:18][CH2:19][CH2:20][NH:21][C:22]([N:17]([CH2:13][CH:14]([CH3:16])[CH3:15])[CH:2]1[O:10][C@H:9]([CH2:11][OH:12])[C@H:7]([OH:8])[C@H:5]([OH:6])[C@H:3]1[OH:4])=[O:23]

Participants

4

Reactant 3

HCID 6558IsobutylamineHCID 160352-Chloroethyl isocyanateHCID 3037556(2R,3S,4S,5R)-2,3,4,5,6-pentahydroxyhexanal

Product 1

HCID 54093436HCID 54093436, compoundYield 80.8%

Procedure

A mixture of 3.6 g of D-galactose, 2.0 g of isobutylamine and 2.5 g of 2-chloroethyl isocyanate are treated in the same manner as described in Example 5-(1). 5.5 g of 1-(2-chloroethyl)-3-isobutyl-3-D-galactopyranosylurea are thereby obtained as colorless caramel.

Workup

  1. additionare treated in the same manner

Sources & evidence

ORD record
ord-947a742839304a02b5d90a67e6459ed9
Source dataset
uspto-grants-1980_01
Patent number
US04182757

Reaction notes

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