Methylamine → HCID 54050138, compound

HRID 2051830Notes

Reaction equation

HRID 2051830 reaction equation
O=[CH:2][C@@H:3]([C@@H:5]([C@@H:7]([CH2:9][OH:10])[OH:8])[OH:6])[OH:4].[CH3:11][NH2:12].[Cl:13][CH2:14][CH2:15][N:16]=[C:17]=[O:18]>>[Cl:13][CH2:14][CH2:15][NH:16][C:17]([N:12]([CH3:11])[CH:2]1[O:8][C@H:7]([CH2:9][OH:10])[C@@H:5]([OH:6])[C@H:3]1[OH:4])=[O:18]

Participants

4

Reactant 3

HCID 6329MethylamineHCID 160352-Chloroethyl isocyanateHCID 5311110Aldehydo-D-ribose

Product 1

HCID 54050138HCID 54050138, compoundYield 74.5%

Procedure

3.0 g of D-ribose, 1.0 g of methylamine and 2.5 g of 2-chloroethyl isocyanate are treated in the same manner as described in Example 1-(1). 4.0 g of 1-(2-chloroethyl)-3-methyl-3-D-ribofuranosylurea are thereby obtained as colorless caramel.

Sources & evidence

ORD record
ord-64d4a67bda204b0187aaec32cd444914
Source dataset
uspto-grants-1980_01
Patent number
US04182757

Reaction notes

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