反应详情

A mixture of 18.7 g of 2-(2-naphthyloxy)ethanol O-methanesulfonate and 23.6 g of ethyl p-aminobenzoate is heated in 300 ml of hexamethylphosphoramide at 110° C. for 16 hours. The mixture is cooled, diluted with water, and worked up as described in Example 3 to give the crystalline product. Recrystallization from ethanol gives crystals, mp 158°-162° C.

1. temperatureThe mixture is cooled
2. customto give the crystalline product
3. customRecrystallization from ethanol
4. customgives crystals, mp 158°-162° C.