HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium Hydroxide → 4-{[2-(Thiophen-2-yl)ethyl]amino}benzoic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium Hydroxide | HCID 14797 | — |
| Reactant | Ethyl 4-{[2-(thiophen-2-yl)ethyl]amino}benzoate | HCID 13079686 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 4-{[2-(Thiophen-2-yl)ethyl]amino}benzoic acid | HCID 13079685 | — |
Reaction Steps
A mixture of 29.7 g of ethyl p-[2-(2-thienyl)ethylamino]benzoate and 29 g of potassium hydroxide in 200 ml of 95% ethanol is refluxed for 3 hours. The mixture is worked up as described in Example 4 to give the product, mp 161°-163° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04182776 |
| Source dataset | uspto-grants-1980_01 |
| ORD ID | ord-ba5a26e36bb14055959012221e18e860 |
| Source note | uspto-grants-1980_01 |