Triethylamine → HCID 21480157, compound

Participants

Reaction Steps

To a solution of 8.5 g. of 2-(4-chlorophenoxy)-1-propanol, 9.2 g. of triethylamine and 250 ml. of dichloromethane chilled to -5° C. are added dropwise 5.7 g of methanesulfonyl chloride. The solution is allowed to stand at room temperature for 1 hour and is washed with 100 ml portions of water, 10% hydrochloric acid, saturated sodium bicarbonate and saturated sodium chloride. The organic layer is dried (magnesium sulfate) and the solvent removed under vacuum to give 11.3 g of product as an oil.

Provenance & Evidence