Formic Acid → HCID 20378790, compound

HRID 2052133Notes

Reaction equation

HRID 2052133 reaction equation
[CH:1]1[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[CH:4]=[CH:3][C:2]=1[C:11]([NH2:13])=[O:12].[P:14]([Cl:19])(Cl)(Cl)(Cl)[Cl:15].Cl.C(O)=[O:22]>C(Cl)(Cl)(Cl)Cl>[Cl:15][P:14]([Cl:19])([NH:13][C:11]([C:2]1[CH:3]=[CH:4][C:5]2[C:10](=[CH:9][CH:8]=[CH:7][CH:6]=2)[CH:1]=1)=[O:12])=[O:22]

Participants

6

Reactant 4

HCID 284Formic AcidHCID 313Hydrochloric AcidHCID 24819Phosphorus pentachlorideHCID 75245Naphthalene-2-carboxamide

Product 1

HCID 20378790HCID 20378790, compound

Reagents, catalysts & solvents 1

HCID 5943Carbon TetrachlorideSolvent

Procedure

A mixture of 40 g (0.23 mole) of 2-naphthalene carboxamide, 48.7 g (0.23 mole) of phosphorus pentachloride and 400 ml of AR carbon tetrachloride was heated at 70° for 30 min. at which time the HCl evolution had ceased. It was cooled to 30° and 11.1 g (0.23 mole) of 97% formic acid added dropwise. Continued to stir for 30 min., then filtered, washed with AR carbon tetrachloride and air-dried to give 43 g, m.p. 110°-111°.

Workup

  1. temperatureIt was cooled to 30°
  2. filtrationfiltered
  3. washwashed with AR carbon tetrachloride
  4. customair-dried
  5. customto give 43 g, m.p. 110°-111°

Sources & evidence

ORD record
ord-b5b06bbed27e455c89d4099d81315225
Source dataset
uspto-grants-1980_01
Patent number
US04182881

Reaction notes

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