Thionyl Chloride → 4-Butoxybenzoyl chloride

HRID 2052139Notes

Reaction equation

HRID 2052139 reaction equation
[CH2:1]([O:5][C:6]1[CH:14]=[CH:13][C:9]([C:10](O)=[O:11])=[CH:8][CH:7]=1)[CH2:2][CH2:3][CH3:4].S(Cl)([Cl:17])=O>>[CH2:1]([O:5][C:6]1[CH:14]=[CH:13][C:9]([C:10]([Cl:17])=[O:11])=[CH:8][CH:7]=1)[CH2:2][CH2:3][CH3:4]

Participants

3

Reactant 2

HCID 24386Thionyl ChlorideHCID 729714-Butoxybenzoic acid

Product 1

HCID 1185614-Butoxybenzoyl chloride

Procedure

Heated at reflux a solution of 75 g (0.39 mole) of 4-n-butoxybenzoic acid in 250 ml of thionyl chloride for 3 hrs. Removed by vacuum distillation the excess thionyl chloride to give 84 g of a brown colored liquid.

Workup

  1. temperatureHeated
  2. customRemoved by vacuum distillation the excess thionyl chloride

Sources & evidence

ORD record
ord-40f68a5341a644bc90103b090e74f8ba
Source dataset
uspto-grants-1980_01
Patent number
US04182881

Reaction notes

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