Ammonia → 4-butoxybenzamide

HRID 2052140Notes

Reaction equation

HRID 2052140 reaction equation
[CH2:1]([O:5][C:6]1[CH:14]=[CH:13][C:9]([C:10](Cl)=[O:11])=[CH:8][CH:7]=1)[CH2:2][CH2:3][CH3:4].[NH3:15]>C(Cl)(Cl)Cl>[CH2:1]([O:5][C:6]1[CH:14]=[CH:13][C:9]([C:10]([NH2:15])=[O:11])=[CH:8][CH:7]=1)[CH2:2][CH2:3][CH3:4]

Participants

4

Reactant 2

HCID 222AmmoniaHCID 1185614-Butoxybenzoyl chloride

Product 1

HCID 43063154-butoxybenzamide

Reagents, catalysts & solvents 1

HCID 6212ChloroformSolvent

Procedure

Chilled to 20°, a solution of 84 g (0.39 mole) of a solution of 4-n-butoxybenzoyl chloride in 700 ml of AR chloroform, then saturated with anhydrous ammonia. The mixture was stirred for 20 min. to 0°, then the white precipitate collected, washed with cold water and oven-dried to 60° to give 76 g, m.p. shrinks 160°, melts 162°-164°.

Workup

  1. temperatureChilled to 20°
  2. customthe white precipitate collected
  3. washwashed with cold water
  4. customoven-dried to 60°
  5. customto give 76 g
  6. customshrinks 160°
  7. custommelts 162°-164°

Sources & evidence

ORD record
ord-1506df6ddfcf4c86b4c1a0c86eccd7f3
Source dataset
uspto-grants-1980_01
Patent number
US04182881

Reaction notes

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