2,4,6-Trimethylbenzoic acid → 2,4,6-Trimethylbenzoyl chloride

HRID 2052148Notes

Reaction equation

HRID 2052148 reaction equation
[CH3:1][C:2]1[CH:10]=[C:9]([CH3:11])[CH:8]=[C:7]([CH3:12])[C:3]=1[C:4](O)=[O:5].S(Cl)([Cl:15])=O>>[CH3:1][C:2]1[CH:10]=[C:9]([CH3:11])[CH:8]=[C:7]([CH3:12])[C:3]=1[C:4]([Cl:15])=[O:5]

Participants

3

Reactant 2

HCID 101942,4,6-Trimethylbenzoic acidHCID 24386Thionyl Chloride

Product 1

HCID 970382,4,6-Trimethylbenzoyl chloride

Procedure

A solution of 50 g (0.3 mole) of 2,4,6-trimethylbenzoic acid and 150 ml of thionyl chloride was heated at reflux for 3 hrs. The excess thionyl cloride was removed by vacuum distillation to give 53.5 g of an amber colored liquid.

Workup

  1. temperatureat reflux for 3 hrs
  2. customThe excess thionyl cloride was removed by vacuum distillation

Sources & evidence

ORD record
ord-3f784c36f2e348d18b60c7396f787c09
Source dataset
uspto-grants-1980_01
Patent number
US04182881

Reaction notes

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