Formic Acid → HCID 20378789, compound

HRID 2052149Notes

Reaction equation

HRID 2052149 reaction equation
[CH3:1][C:2]1[CH:10]=[C:9]([CH3:11])[CH:8]=[C:7]([CH3:12])[C:3]=1[C:4]([NH2:6])=[O:5].[P:13]([Cl:18])(Cl)(Cl)(Cl)[Cl:14].C(O)=[O:20]>C(Cl)(Cl)(Cl)Cl>[Cl:14][P:13]([Cl:18])([NH:6][C:4](=[O:5])[C:3]1[C:7]([CH3:12])=[CH:8][C:9]([CH3:11])=[CH:10][C:2]=1[CH3:1])=[O:20]

Participants

5

Reactant 3

HCID 284Formic AcidHCID 24819Phosphorus pentachlorideHCID 2466862,4,6-trimethylbenzamide

Product 1

HCID 20378789HCID 20378789, compound

Reagents, catalysts & solvents 1

HCID 5943Carbon TetrachlorideSolvent

Procedure

A suspension of 21 g (0.13 mole) of 2,4,6-trimethylbenzamide and 26.8 g (0.13 mole) of phosphorus pentachloride in 200 ml of AR carbon tetrachloride was heated at 70° for 30 min. The solution was cooled to 30° and 6.1 g (0.13 mole) of 97% formic acid added dropwise. Stirred for another 20 min., then filtered, washed with AR carbon tetrachloride and air-dried to give 20.5 g, m.p. 109°-110°.

Workup

  1. temperaturewas heated at 70° for 30 min
  2. temperatureThe solution was cooled to 30°
  3. filtrationfiltered
  4. washwashed with AR carbon tetrachloride
  5. customair-dried
  6. customto give 20.5 g, m.p. 109°-110°

Sources & evidence

ORD record
ord-1ce8683b35fe4625a85aff29ac4e6f07
Source dataset
uspto-grants-1980_01
Patent number
US04182881

Reaction notes

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