HuagongsheHuagongshe Chemistry Print Report · For research reference only
Dimethylcarbamoyl Chloride → HCID 20377181, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Dimethylcarbamoyl Chloride | HCID 6598 | — |
| Reactant | 2-Amino-4,5-dimethyl-1,3-thiazole | HCID 73238 | — |
| Reactant | Aluminum(III) Chloride | HCID 6451240 | — |
| Solvent | O-Xylene | HCID 7237 | — |
| Product | HCID 20377181 | HCID 20377181 | 91.5% |
Reaction Steps
Using 2-amino-4,5-dimethylthiazole (1.28 g), N,N-dimethylcarbamoyl chloride (1.29 g), aluminum chloride (1.60 g), and xylene (40 ml), the reaction is run as in Example 1, whereby 1,1-dimethyl-3-(4,5-dimethyl-2-thiazolyl)urea (1.82 g) is obtained. Yield is 91.5%. Melting point is 202.5° to 204° C. (after recrystallization from ethyl acetate).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04183856 |
| Source dataset | uspto-grants-1980_01 |
| ORD ID | ord-0c0d9af78a8e4309815ae68b6bb67f27 |
| Source note | uspto-grants-1980_01 |