HuagongsheHuagongshe Chemistry Print Report · For research reference only
Dimethylcarbamoyl Chloride → N-(2-Benzothiazolyl)-N',N'-dimethylurea
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Dimethylcarbamoyl Chloride | HCID 6598 | — |
| Reactant | Benzo(d)thiazol-2-amine | HCID 8706 | — |
| Reactant | Aluminum(III) Chloride | HCID 6451240 | — |
| Solvent | Trichloroethylene | HCID 6575 | — |
| Product | N-(2-Benzothiazolyl)-N',N'-dimethylurea | HCID 99155 | 97.7% |
Reaction Steps
Using 2-aminobenzothiazole (1.50 g), N,N-dimethylcarbamoyl chloride (1.29 g), aluminum chloride (1.60 g), and trichloroethylene (40 ml), the reaction is effected as in Example 1, except that the reflux is carried out for 40 hours. Thus, 1,1-dimethyl-3-(2-benzothiazolyl)urea (2.16 g) is obtained. Yield is 97.7%. Melting point is higher than 300° C. (after recrystallization from ethanol).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04183856 |
| Source dataset | uspto-grants-1980_01 |
| ORD ID | ord-b1da622f11aa4dbd85fc654d4a51ced1 |
| Source note | uspto-grants-1980_01 |