3-Isoxazolamine, 5-(1,1-dimethylethyl)- → N'-(5-tert-Butyl-1,2-oxazol-3-yl)-N-methyl-N-prop-2-en-1-ylurea

HRID 2052207Notes

Reaction equation

HRID 2052207 reaction equation
[NH2:1][C:2]1[CH:6]=[C:5]([C:7]([CH3:10])([CH3:9])[CH3:8])[O:4][N:3]=1.[CH2:11]([N:14]([CH3:18])[C:15](Cl)=[O:16])[CH:12]=[CH2:13]>>[CH2:11]([N:14]([CH3:18])[C:15]([NH:1][C:2]1[CH:6]=[C:5]([C:7]([CH3:10])([CH3:9])[CH3:8])[O:4][N:3]=1)=[O:16])[CH:12]=[CH2:13]

Participants

3

Reactant 2

HCID 1714733-Isoxazolamine, 5-(1,1-dimethylethyl)-HCID 2215586451493-18-6

Product 1

HCID 13373599N'-(5-tert-Butyl-1,2-oxazol-3-yl)-N-methyl-N-prop-2-en-1-ylureaYield 90.5%

Procedure

Using 3-amino-5-t-butylisoxazole and N-allyl-N-methylcarbamoyl chloride, the reaction is effected as in Example 1, whereby 1-allyl-1-methyl-3-(5-t-butyl-3-isoxazolyl)urea is obtained. Yield is 90.5%. Melting point is 90.0° to 91.0° C.

Sources & evidence

ORD record
ord-dfc7a98445cd4c4da4b2bcaa11a26b57
Source dataset
uspto-grants-1980_01
Patent number
US04183856

Reaction notes

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