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HRID2052220

反应详情

EQUATION

反应方程式

HRID 2052220 的结构方程式

REACTANTS

反应物

4
结构：NCc1ccccc1
HCID7504

Benzylamine

C7H9N

结构：O=C(O)[C@H]1C[C@H]1C(=O)O
HCID726455

(1R,2S)-rel-Cyclopropane-1,2-dicarboxylic acid

C5H6O4

结构：O=C(O)C1NCC2CC21
HCID3779453

未命名化合物

结构：C1NCC2CC12
HCID13150523

3-Azabicyclo[3.1.0]hexane

C5H9N

PRODUCTS

生成物

1
结构：O=C1C2CC2C(=O)N1Cc1ccccc1
HCID2764586

3-benzyl-3-azabicyclo[3.1.0]hexane-2,4-dione

C12H11NO2

PROCEDURE

实验过程

3-Azabicyclo(3.1.0)hexane, a precursor for preparing 3-azabicyclo(3.1.0)hexane-2-carboxylic acid, a plant gametocide, is prepared by (a) treating cis-1,2-cyclopropanedicarboxylic acid with benzylamine, to form 3-(benzyl)-3-azabicyclo(3.1.0)hexane-2,4-dione, (b) selectively reducing the dione to 3-(benzyl)-3-azabicyclo(3.1.0)hexane, and (c) hydrogenolysis of that compound to 3-azabicyclo(3.1.0)hexane.