HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → 4-[(8-Phenyloctyl)amino]benzoic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Potassium Hydroxide | HCID 14797 | — |
| Reactant | Ethyl 4-[(8-phenyloctyl)amino]benzoate | HCID 13079665 | — |
| Reactant | Water ethanol | HCID 19096565 | — |
| Solvent | Water | HCID 962 | — |
| Product | 4-[(8-Phenyloctyl)amino]benzoic acid | HCID 13079664 | — |
Reaction Steps
A mixture of 7 g. of ethyl p-[(8-phenyloctyl)amino]benzoate (prepared as described in Example 32), 7 g. of potassium hydroxide and 100 ml. of ethanol-water (9:1) is refluxed for 3.5 hours. The mixture is acidified while hot with concentrated hydrochloric acid, diluted with water, chilled and filtered. The solid is washed with water to give off-white crystals, m.p. 113°-115° C. Recrystallization from ethanol gives white crystals, m.p. 113°-115° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04185115 |
| Source dataset | uspto-grants-1980_01 |
| ORD ID | ord-0496fc516e454dcb8019e7fd53d37faf |
| Source note | uspto-grants-1980_01 |