反应详情

A mixture of 7 g. of ethyl p-[(8-phenyloctyl)amino]benzoate (prepared as described in Example 32), 7 g. of potassium hydroxide and 100 ml. of ethanol-water (9:1) is refluxed for 3.5 hours. The mixture is acidified while hot with concentrated hydrochloric acid, diluted with water, chilled and filtered. The solid is washed with water to give off-white crystals, m.p. 113°-115° C. Recrystallization from ethanol gives white crystals, m.p. 113°-115° C.

1. additionA mixture of 7 g
2. temperaturechilled
3. filtrationfiltered
4. washThe solid is washed with water
5. customto give off-white crystals, m.p. 113°-115° C
6. customRecrystallization from ethanol
7. customgives white crystals, m.p. 113°-115° C.