HuagongsheHuagongshe Chemistry Print Report · For research reference only
Colchicine → Thiocholchicine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Colchicine | HCID 6167 | — |
| Reactant | Sodium methanethiolate | HCID 4378561 | — |
| Solvent | Water | HCID 962 | — |
| Product | Thiocholchicine | HCID 17648 | — |
Reaction Steps
Colchicine (1.25 mmole) was dissolved in 10.0 mL of water to which was added sodium methanethiolate (7.13 mmol). The yellow solution was stirred for 24 hours, then extracted 3× with ETOH:Chloroform (1:1), then evaporated to yield the desired compound as yellow crystals.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07326685B2 |
| Source dataset | uspto-grants-2008_02 |
| ORD ID | ord-9847e97939a745d88de102c31d00ce24 |
| Source note | uspto-grants-2008_02 |