HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sulfuryl chloride → 4-amino-3-chloro-5-(trifluoromethyl)benzoic Acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sulfuryl chloride | HCID 24648 | — |
| Reactant | 4-Amino-3-(trifluoromethyl)benzoic acid | HCID 3254286 | — |
| Solvent | Chloroform | HCID 6212 | — |
| Product | 4-amino-3-chloro-5-(trifluoromethyl)benzoic Acid | HCID 4643549 | — |
Reaction Steps
7.8 g (40 mmol) of 4-amino-5-trifluoromethylbenzoic acid in 80 ml of chloroform are placed in a 500 ml round-bottomed flask in the presence of 9.97 ml (50 mmol) of sulphuryl chloride, and the mixture is stirred under reflux overnight.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07326722B2 |
| Source dataset | uspto-grants-2008_02 |
| ORD ID | ord-b5ef6b71af124755b154b59653141be3 |
| Source note | uspto-grants-2008_02 |