HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethyl 2-(3-aminophenoxy)acetate → (3-{[6-(3-Chloro-phenyl)-pyridine-2-carbonyl]-amino}-phenoxy)-acetic acid ethyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethyl 2-(3-aminophenoxy)acetate | HCID 412308 | — |
| Reactant | 6-(3-Chlorophenyl)picolinic acid | HCID 24730135 | — |
| Product | (3-{[6-(3-Chloro-phenyl)-pyridine-2-carbonyl]-amino}-phenoxy)-acetic acid ethyl ester | HCID 59654828 | — |
Reaction Steps
Carboxylic acid (136)(44 mg, 0.19 mmol) was coupled with aniline (64)(40 mg, 0.2 mmol) using Method D. The residue was purified by column chromatography eluting with 10% EtOAc in heptane to give the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07326732B2 |
| Source dataset | uspto-grants-2008_02 |
| ORD ID | ord-7b75753f81b249a1928e0672a9b04263 |
| Source note | uspto-grants-2008_02 |