Pentylamine → HCID 178446284, compound

HRID 2053296Notes

Reaction equation

CS[C:3]1[S:4]/[C:5](=[CH:9]\[C:10]2[CH:11]=[C:12]3[C:17](=[CH:18][CH:19]=2)[N:16]=[CH:15][CH:14]=[CH:13]3)/[C:6](=[O:8])[N:7]=1.[CH2:20]([NH2:25])[CH2:21][CH2:22][CH2:23][CH3:24].CCN(C(C)C)C(C)C>>[CH2:20]([NH:25][C:3]1[S:4]/[C:5](=[CH:9]\[C:10]2[CH:11]=[C:12]3[C:17](=[CH:18][CH:19]=2)[N:16]=[CH:15][CH:14]=[CH:13]3)/[C:6](=[O:8])[N:7]=1)[CH2:21][CH2:22][CH2:23][CH3:24]

Participants

Reactant 3

HCID 8060Pentylamine

HCID 81531Diisopropylethylamine

HCID 58585737(5Z)-2-(methylthio)-5-(6-quinolinylmethylidene)-1,3-thiazol-4(5H)-one

Product 1

HCID 178446284HCID 178446284, compound

Procedure

Similar procedure as described in example 1b was used, starting from 2-methylsulfanyl-5-[1-quinolin-6-yl-meth-(Z)-ylidene]-thiazol-4-one, pentylamine and DIEA to give 2-pentylamino-5-[1-quinolin-6-yl-meth-(Z)-ylidene]-thiazol-4-one. LC-MS m/e 326 (MH+).

Sources & evidence

ORD record: ord-4bf28f3030b54a05ad16fbe6caa51310
Source dataset: uspto-grants-2008_02
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07326786B2

Reaction notes

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