HuagongsheHuagongshe Chemistry Print Report · For research reference only
Diisopropylethylamine → HCID 178518163, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Diisopropylethylamine | HCID 81531 | — |
| Reactant | (1R,2S)-(+)-cis-1-Amino-2-indanol | HCID 2725045 | — |
| Reactant | (5Z)-2-(methylthio)-5-(6-quinolinylmethylidene)-1,3-thiazol-4(5H)-one | HCID 58585737 | — |
| Product | HCID 178518163 | HCID 178518163 | — |
Reaction Steps
Similar procedure as described in example 1b was used, starting from 2-methylsulfanyl-5-[1-quinolin-6-yl-meth-(Z)-ylidene]-thiazol-4-one, (1R,2S)-(−)-2-hydroxy-indan-1-ylamine and DIEA to give 2-((1R,2S)-2-hydroxy-indan-1-ylamino)-5-[1-quinolin-6-yl-meth-(Z)-ylidene]-thiazol-4-one. LC-MS m/e 388 (MH+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07326786B2 |
| Source dataset | uspto-grants-2008_02 |
| ORD ID | ord-8c8234f3658e412ab277a29bc32a7112 |
| Source note | uspto-grants-2008_02 |