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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2053325Generated: November 2, 2026

Diisopropylethylamine → HCID 178518193, compound

https://huagongshe.com/reaction/2053325

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDiisopropylethylamineHCID 81531—
Reactant(R)-2-Amino-2-(4-fluorophenyl)ethanolHCID 10583003—
Reactant(5Z)-2-(methylthio)-5-(6-quinolinylmethylidene)-1,3-thiazol-4(5H)-oneHCID 58585737—
ProductHCID 178518193HCID 178518193—

Reaction Steps

Then the similar procedure as described in example 1b was used, starting from 2-methylsulfanyl-5-[1-quinolin-6-yl-meth-(Z)-ylidene]-thiazol-4-one, (R)-4-fluoro-phenylglycinol and DIEA to give 2-[(R)-1-(4-fluoro-phenyl)-2-hydroxy-ethylamino]-5-[1-quinolin-6-yl-meth-(Z)-ylidene]-thiazol-4-one. LC-MS m/e 394 (MH+).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07326786B2
Source datasetuspto-grants-2008_02
ORD IDord-90f85f49fcbc498b9e2e6cff9e9397ea
Source noteuspto-grants-2008_02