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HRID2053336

反应详情

EQUATION

反应方程式

HRID 2053336 的结构方程式

REACTANTS

反应物

3
结构：CCN(C(C)C)C(C)C
HCID81531

Diisopropylethylamine

C8H19N

结构：Cl.NC(=O)[C@H](N)c1ccccc1
HCID16216957

(2R)-2-Amino-2-phenylacetamide--hydrogen chloride (1/1)

C8H11ClN2O

结构：CSC1=NC(=O)/C(=C/c2ccc3ncccc3c2)S1
HCID58585737

未命名化合物

PRODUCTS

生成物

1
结构：NC(=O)[C@H](NC1=NC(=O)/C(=C/c2ccc3ncccc3c2)S1)c1ccccc1
HCID178514016

未命名化合物

PROCEDURE

实验过程

Similar procedure as described in example 1b was used, starting from 2-methylsulfanyl-5-[1-quinolin-6-yl-meth-(Z)-ylidene]-thiazol-4-one, (R)-2-amino-2-phenyl-acetamide hydrochloride and DIEA to give (R)-2-{4-oxo-5-[1-quinolin-6-yl-meth-(Z)-ylidene]-4,5-dihydro-thiazol-2-ylamino}-2-phenyl-acetamide. LC-MS m/e 389 (MH+).