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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2053341Generated: October 30, 2026

Phenylglycine, D- → HCID 178518198, compound

https://huagongshe.com/reaction/2053341

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPhenylglycine, D-HCID 70134—
ReactantDiisopropylethylamineHCID 81531—
Reactant(5Z)-2-(methylthio)-5-(6-quinolinylmethylidene)-1,3-thiazol-4(5H)-oneHCID 58585737—
ProductHCID 178518198HCID 178518198—

Reaction Steps

Similar procedure as described in example 1b was used, starting from 2-methylsulfanyl-5-[1-quinolin-6-yl-meth-(Z)-ylidene]-thiazol-4-one, D-phenylglycine and DIEA to give (R)-{4-oxo-5-[1-quinolin-6-yl-meth-(Z)-ylidene]-4,5-dihydro-thiazol-2-ylamino}-phenyl-acetic acid. LC-MS m/e 390 (MH+).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07326786B2
Source datasetuspto-grants-2008_02
ORD IDord-728662028a0e47228aae2dc73d79d9d2
Source noteuspto-grants-2008_02