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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2053348Generated: October 30, 2026

Diisopropylethylamine → HCID 178518172, compound

https://huagongshe.com/reaction/2053348

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDiisopropylethylamineHCID 81531—
Reactantrac-(1R,2R)-2-aminocyclopentan-1-olHCID 10464306—
Reactant(5Z)-2-(methylthio)-5-(6-quinolinylmethylidene)-1,3-thiazol-4(5H)-oneHCID 58585737—
ProductHCID 178518172HCID 178518172—

Reaction Steps

Similar procedure as described in example 1b was used, starting from 2-methylsulfanyl-5-[1-quinolin-6-yl-meth-(Z)-ylidene]-thiazol-4-one, (1R,2R)-2-hydroxy-cyclopentylamine and DIEA to give 2-((1R,2R)-2-hydroxy-cyclopentylamino)-5-[1-quinolin-6-yl-meth-(Z)-ylidene]-thiazol-4-one. LC-MS m/e 340 (MH+).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07326786B2
Source datasetuspto-grants-2008_02
ORD IDord-ad4c813fa3384e60b04c9b626c0e0c61
Source noteuspto-grants-2008_02