3,3,3-Trifluoropropyne → HCID 22042604, compound

HRID 2053668Notes

Reaction equation

HRID 2053668 reaction equation
[CH3:1][N:2]([C:12]1[CH:17]=[CH:16][C:15]([C:18](=[O:23])[C:19]([F:22])([F:21])[F:20])=[CH:14][CH:13]=1)[S:3]([C:6]1[CH:11]=[CH:10][CH:9]=[CH:8][CH:7]=1)(=[O:5])=[O:4].[F:24][C:25]([F:29])([F:28])[C:26]#[CH:27]>>[CH3:1][N:2]([C:12]1[CH:17]=[CH:16][C:15]([C:18]([OH:23])([C:19]([F:21])([F:22])[F:20])[C:27]#[C:26][C:25]([F:29])([F:28])[F:24])=[CH:14][CH:13]=1)[S:3]([C:6]1[CH:7]=[CH:8][CH:9]=[CH:10][CH:11]=1)(=[O:5])=[O:4]

Participants

3

Reactant 2

HCID 695783,3,3-TrifluoropropyneHCID 22042580HCID 22042580, compound

Product 1

HCID 22042604HCID 22042604, compound

Procedure

The compound was prepared from N-methyl-N-(4-trifluoroacetyl-phenyl)-benzenesulfonamide (Example 22, Step A) and 3,3,3-trifluoroprop-1-yne following the procedure described in Example 29. 1H NMR (CDCl3) δ 3.19 (s, 3 H), 4.30 (br s, 1H), 7.11-7.63 (m, 9 H). Mass Spectrum (CI+) m/e=438 (M+1).

Sources & evidence

ORD record
ord-fa4dc769a0724332a4909b74a8744ad1
Source dataset
uspto-grants-2008_02
Patent number
US07326812B2

Reaction notes

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