HuagongsheHuagongshe Chemistry Print Report · For research reference only
N'-tert-butoxycarbonyl-C-(5-chloro-1H-benzimidazol-2-yl)methylamine → HCID 178510549, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | N'-tert-butoxycarbonyl-C-(5-chloro-1H-benzimidazol-2-yl)methylamine | HCID 69311165 | — |
| Solvent | Hydrochloric Acid | HCID 313 | — |
| Product | HCID 178510549 | HCID 178510549 | — |
Reaction Steps
4.62 g (16.398 mmol) N′-tert-butoxycarbonyl-C-(5-chloro-1H-benzimidazol-2-yl)methylamine are dissolved in 100 mL saturated ethanolic hydrogen chloride solution and stirred for 2 hours at ambient temperature. Then all the volatile constituents are removed under reduced pressure and the crude product is further reacted. Yield: quantitative; Rf value: 0.35 (silica gel; petroleum ether/ethyl acetate=8:2).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07326791B2 |
| Source dataset | uspto-grants-2008_02 |
| ORD ID | ord-7478f4d72a2244f0bcd4683b650e5575 |
| Source note | uspto-grants-2008_02 |