HuagongsheHuagongshe Chemistry Print Report · For research reference only
Dichloromethane ethanol → HCID 43114481, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Dichloromethane ethanol | HCID 21584144 | — |
| Reactant | HCID 69314702 | HCID 69314702 | — |
| Solvent | Hydrochloric Acid | HCID 313 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 43114481 | HCID 43114481 | — |
Reaction Steps
1.35 g (4.302 mmol) of rac.-N-acetyl-1-(5-chlorobenzimidazol-2-yl)-2-phenylethylamine is placed in a mixture of 20 mL of 4 molar hydrochloric acid and 15 mL of methanol and the mixture is refluxed for 2 hours. Then all the volatile constituents are removed under reduced pressure. The crude product is further reacted directly. Rf value: 0.50 (silica gel; dichloromethane/ethanol=8:2).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07326791B2 |
| Source dataset | uspto-grants-2008_02 |
| ORD ID | ord-067e72a1f7064a1e999bd17879db5745 |
| Source note | uspto-grants-2008_02 |