HuagongsheHuagongshe Chemistry Print Report · For research reference only
Chlorine → HCID 178427135, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Chlorine | HCID 24526 | — |
| Reactant | 3-Methyl 4-(pyrrolidin-1-ylcarbonyl)benzoic acid | HCID 12068686 | — |
| Reactant | HCID 178511783 | HCID 178511783 | — |
| Solvent | Dichloromethane methanol | HCID 21226129 | — |
| Product | HCID 178427135 | HCID 178427135 | 55% |
Reaction Steps
Prepared analogously to Example 10d from (S)-1-(5-chloro-1H-benzimidazol-2-yl)-2-(1H-imidazol-4-yl)ethylamine and 3-methyl-4-(pyrrolidin-1-ylcarbonyl)benzoic acid. Yield: 55% of theory. Rf value: 0.72 (silica gel; dichloromethane/methanol=4:1); C25H25ClN6O2 (476.97); mass spectrum: (M+H)+=477/479 (chlorine isotope).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07326791B2 |
| Source dataset | uspto-grants-2008_02 |
| ORD ID | ord-b54d78bd49384fc9a9b3c8e3ab074b56 |
| Source note | uspto-grants-2008_02 |