HuagongsheHuagongshe Chemistry Print Report · For research reference only
Triethylamine → HCID 178470444, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | O-(Benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate | HCID 2733207 | — |
| Reactant | HCID 69314856 | HCID 69314856 | — |
| Reactant | HCID 178510880 | HCID 178510880 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Solvent | Ethyl Acetate | HCID 8857 | — |
| Product | HCID 178470444 | HCID 178470444 | 52% |
Reaction Steps
Prepared analogously to Example 1g from 4-[3-(ethoxycarbonyl)-5,6-dihydro-4H-cyclopentapyrazol-1-yl]-3-trifluoromethylbenzoic acid, TBTU, triethylamine, and (5-chloro-1H-benzimidazol-2-yl)ethylamine in tetrahydrofuran. Yield: 52%; Rf value: 0.40 (silica gel; ethyl acetate);C26H23ClF3N5O3 (545.95); mass spectrum: (M+H)+=546.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07326791B2 |
| Source dataset | uspto-grants-2008_02 |
| ORD ID | ord-ed569dd216eb45c8b579cdb802e6aa7f |
| Source note | uspto-grants-2008_02 |