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HRID2053963

反应详情

EQUATION

反应方程式

HRID 2053963 的结构方程式

REACTANTS

反应物

4
结构：ClCl
HCID24526

Chlorine

Cl2

结构：CCN(C(C)C)C(C)C
HCID81531

Diisopropylethylamine

C8H19N

结构：CN(C)CCC1CCCCN1
HCID296295

2-(2-Dimethylaminoethyl)piperidine

C9H20N2

结构：CC(NC(=O)c1ccc(C(=O)O)c(Cl)c1)c1nc2cc(Cl)ccc2[nH]1
HCID178464831

未命名化合物

PRODUCTS

生成物

1
结构：CC(NC(=O)c1ccc(C(=O)N2CCCCC2CCN(C)C)c(Cl)c1)c1nc2cc(Cl)ccc2[nH]1
HCID178464800

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

1
结构：CS(C)=O
溶剂HCID679

Dimethyl sulfoxide

C2H6OS

PROCEDURE

实验过程

Prepared analogously to Example 1d from rac.-2-chloro-4-{N-[1-(5-chloro-1H-benzimidazol-2-yl)ethyl]aminocarbonyl}benzoic acid, rac.-2-(2-dimethylaminoethyl)piperidine, PFTU, and diisopropylethylamine in DMSO at ambient temperature. HPLC-MS results: retention time: 4.01 minutes; C26H31Cl2N5O2 (516.47); mass spectrum: (M−H)−=515/517 (chlorine isotope).

WORKUP

后处理

  1. customHPLC-MS results