Tetrahydrofuran → HCID 67385373, compound

HRID 205409Notes

Reaction equation

[CH2:102]1[O:103][CH2:104][CH2:105][CH2:106]1.[CH2:41]([O:42][C:43]([c:44]1[n:45][c:46]([Br:47])[s:48][cH:49]1)=[O:50])[CH3:51].[CH2:52]([CH3:53])[O:54][C:55](=[O:56])[c:57]1[n:58][c:59]([N:62]2[CH2:63][CH2:64][c:65]3[c:66]2[n:67][c:68]([N:96]2[CH2:97][CH2:98][O:99][CH2:100][CH2:101]2)[n:69][c:70]3-[c:71]2[cH:72][n:73][c:74]([N:77]([CH2:78][c:79]3[cH:80][cH:81][c:82]([O:85][CH3:86])[cH:83][cH:84]3)[CH2:87][c:88]3[cH:89][cH:90][c:91]([O:94][CH3:95])[cH:92][cH:93]3)[n:75][cH:76]2)[s:60][cH:61]1.[CH3:1][O:2][c:3]1[cH:4][cH:5][c:6]([CH2:7][N:8]([CH2:9][c:10]2[cH:11][cH:12][c:13]([O:14][CH3:15])[cH:16][cH:17]2)[c:18]2[n:19][cH:20][c:21](-[c:22]3[c:23]4[c:27]([n:28][c:29]([N:30]5[CH2:31][CH2:32][O:33][CH2:34][CH2:35]5)[n:36]3)[NH:26][CH2:25][CH2:24]4)[cH:37][n:38]2)[cH:39][cH:40]1>>[O:54]=[C:55]([OH:56])[c:57]1[n:58][c:59]([N:62]2[CH2:63][CH2:64][c:65]3[c:66]2[n:67][c:68]([N:96]2[CH2:97][CH2:98][O:99][CH2:100][CH2:101]2)[n:69][c:70]3-[c:71]2[cH:72][n:73][c:74]([N:77]([CH2:78][c:79]3[cH:80][cH:81][c:82]([O:85][CH3:86])[cH:83][cH:84]3)[CH2:87][c:88]3[cH:89][cH:90][c:91]([O:94][CH3:95])[cH:92][cH:93]3)[n:75][cH:76]2)[s:60][cH:61]1

Participants

Reactant 4

HCID 8028Tetrahydrofuran

HCID 353965Ethyl 2-bromo-1,3-thiazole-4-carboxylate

HCID 45258862Bis-(4-methoxybenzyl)-[5-(2-morpholin-4-yl-6,7-dihydro-5H-pyrrolo[2,3-d]pyrimidin-4-yl)-pyrimidin-2-yl]-amine

HCID 67385850HCID 67385850, compound

Product 1

HCID 67385373HCID 67385373, compound

Sources & evidence

ORD record: ord-48b14a1f62ed41b0a8a0cf5e798124b8
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (6/10)
DOI: 10.1039/C8SC04228D

Reaction notes

Loading…