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HRID2054309

反应详情

EQUATION

反应方程式

HRID 2054309 的结构方程式

REACTANTS

反应物

3
结构：CC(=O)c1ccccn1
HCID14286

1-(2-Pyridyl)-1-ethanone

C7H7NO

结构：N#Cc1[nH]cnc1N
HCID78777

5-Amino-1H-imidazole-4-carbonitrile

C4H4N4

结构：O=C(CC(=O)C(F)(F)F)c1ccccn1
HCID2771478

4,4,4-trifluoro-1-(pyridin-2-yl)butane-1,3-dione

C9H6F3NO2

PRODUCTS

生成物

1
结构：N#Cc1ncn2c(C(F)(F)F)cc(-c3ccccn3)nc12
HCID67213352

未命名化合物

收率 47%

PROCEDURE

实验过程

Reaction of 1-pyridin-2-yl-4,4,4-trifluoro-butane-1,3-dione (217 mg, 1.0 mmol), prepared from commercially available 2-acetylpyridine according to general procedure A, and 4-amino-5-cyano-1H-imidazole (108 mg, 1.0 mmol) according to general procedure B yielded the title compound as a yellow solid (135 mg, 47%). MS (ISP) 289.9 [(M+H)+]; mp 205° C.