HuagongsheHuagongshe Chemistry Print Report · For research reference only
Chloroform → HCID 59655772, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Chloroform | HCID 6212 | — |
| Reactant | HCID 59655782 | HCID 59655782 | — |
| Solvent | Benzene | HCID 241 | — |
| Solvent | Hydrochloric Acid | HCID 313 | — |
| Product | 3,4-dihydro-2H-pyran | HCID 8080 | — |
| Product | HCID 59655772 | HCID 59655772 | 63% |
| Product | HCID 59655775 | HCID 59655775 | — |
Reaction Steps
Following the same procedure as for 2-[2-Phthalimido-1-(2,3,5,6-tetrahydropyran-2-yl)oxyethyl]-7-azaindole, from 8c (1.3 g, 3.8 mmol) in CHCl3 (50 ml), 6N HCl in benzene (5 ml) and 2,3-dihydropyrane (1.7 ml, 19 mmol), 4-chloro-2-[2-phthalimido-1-(2,3,5,6-tetrahydropyran-2-yl)oxyethyl]-7-azaindole (1.0 g, 63%) as a diastereomeric mixture (1:1) was obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07329666B2 |
| Source dataset | uspto-grants-2008_02 |
| ORD ID | ord-912be7c518324f59bea3e4e995ef9408 |
| Source note | uspto-grants-2008_02 |