HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrazine hydrate (1:1) → HCID 59655794, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrazine hydrate (1:1) | HCID 24654 | — |
| Reactant | HCID 11379978 | HCID 11379978 | — |
| Reactant | HCID 59655772 | HCID 59655772 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 59655794 | HCID 59655794 | 98.4% |
Reaction Steps
Following the same procedure as for 9a, from 4-Chloro-2-[2-phthalimido-1-(2,3,5,6-tetrahydropyran-2-yl)oxyethyl]-7-azaindole (950 mg, 2.2 mmol) in EtOH (50 ml) and NH2NH2.H2O (250 μl, 4.4 mmol). After a reaction time of 3 h. a diastereomeric mixture (1:1) of 9c (640 mg, 97%/o) was obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07329666B2 |
| Source dataset | uspto-grants-2008_02 |
| ORD ID | ord-b42585eb7dde4b778bda71ab4f61421d |
| Source note | uspto-grants-2008_02 |