HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Hydroxide → 5-Fluoro-2,4-dinitrophenol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | 1,5-Difluoro-2,4-dinitrobenzene | HCID 67598 | — |
| Solvent | Water | HCID 962 | — |
| Product | 5-Fluoro-2,4-dinitrophenol | HCID 15083885 | — |
Reaction Steps
0.41 g of 1,3-difluoro-4,6-dinitrobenzene was dissolved in 8 ml of 0.5 N aqueous sodium hydroxide solution and refluxed for 2 hours. After cooling, it was diluted with water and extracted three times with diethyl ether. The aqueous phase was made acidic by adding 1N hydrochloric acid and extracted with diethyl ether. The organic phase was dried on sodium sulfate and concentrated by evaporation in a vacuum.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07329679B2 |
| Source dataset | uspto-grants-2008_02 |
| ORD ID | ord-c6537bed28614d2da777b036950746fd |
| Source note | uspto-grants-2008_02 |