HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → {4-[2-(4-Fluorophenyl)ethyl]piperazin-1-yl}quinolin-8-ylmethanone, hydrochloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | {4-[2-(4-Fluorophenyl)ethyl]piperazin-1-yl}quinolin-8-ylmethanone | HCID 10155608 | — |
| Solvent | Acetone | HCID 180 | — |
| Product | {4-[2-(4-Fluorophenyl)ethyl]piperazin-1-yl}quinolin-8-ylmethanone, hydrochloride | HCID 131726768 | — |
Reaction Steps
Salt formation by reaction of a solution of {4-[2-(4-fluorophenyl)ethyl]-piperazin-1-yl}quinolin-8-ylmethanone in 30 ml of acetone with 0.2 ml of ethanolic hydrochloric acid gives {4-[2-(4-fluorophenyl)ethyl]piperazin-1-yl}quinolin-8-ylmethanone, hydrochloride, m.p. 219-220.5°.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07329749B2 |
| Source dataset | uspto-grants-2008_02 |
| ORD ID | ord-a085f8b167d342ea9091a8b9998af425 |
| Source note | uspto-grants-2008_02 |