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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 205487Generated: October 29, 2026

1-Amino-4-methylpiperazine → [5-[5-Amino-6-[(2-chloro-3,6-difluorophenyl)methoxy]pyrazin-2-yl]thiophen-2-yl]-(4-methylpiperazin-1-yl)methanone

https://huagongshe.com/reaction/205487

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-Amino-4-methylpiperazineHCID 81349—
Reactant5-[5-Amino-6-[(2-chloro-3,6-difluorophenyl)methoxy]pyrazin-2-yl]thiophene-2-carboxylic acidHCID 21111313—
Product[5-[5-Amino-6-[(2-chloro-3,6-difluorophenyl)methoxy]pyrazin-2-yl]thiophen-2-yl]-(4-methylpiperazin-1-yl)methanoneHCID 21111311—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (6/10)
ORD IDord-fdaf2af932d84db3a67355156d6cbd2b
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (6/10)