HuagongsheHuagongshe Chemistry Print Report · For research reference only
Pyridine → HCID 86597507, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Pyridine | HCID 1049 | — |
| Reactant | Sodium Bicarbonate | HCID 516892 | — |
| Reactant | HCID 11105514 | HCID 11105514 | — |
| Reactant | HCID 86597508 | HCID 86597508 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 86597507 | HCID 86597507 | — |
Reaction Steps
1,3,4,6 tetraacetyl D-glucose (W. E. Dick, Carbohyd. Res., 21, 255-268 (1972)) is dissolved in CH2Cl2 to make a 0.1M solution. 6 eqivalents of pyridine and 3 equivalents of 4-azidobutyryl chloride (S. Kusumoto et. al., Bull. Chem. Soc. Jpn., 59, 1289-1298 (1986)) are added. After several hours, the reaction is poured into saturated NaHCO3, extracted with CH2Cl2, dried over Na2SO4, and concentrated. The residue is purified by flash chromatography to give the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07331920B2 |
| Source dataset | uspto-grants-2008_02 |
| ORD ID | ord-b484409001de4d20923c943ab62b3a36 |
| Source note | uspto-grants-2008_02 |